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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
10.3
Human Site:
Y2105
Identified Species:
17.44
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
Y2105
D
E
D
I
C
N
K
Y
N
G
A
V
L
T
E
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
Y2060
D
E
D
I
C
N
K
Y
N
G
A
V
L
T
E
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
E2009
N
G
G
F
A
A
L
E
L
S
S
R
H
L
N
Dog
Lupus familis
XP_547004
2144
235913
C2036
H
Y
S
D
E
D
I
C
N
K
Y
N
G
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
N2085
Y
S
D
E
D
I
C
N
K
Y
N
G
A
V
L
Rat
Rattus norvegicus
XP_001073292
2181
239558
N2073
Y
S
D
E
D
I
C
N
K
Y
N
G
A
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
L2024
N
K
Y
N
G
A
V
L
T
E
S
A
N
L
H
Chicken
Gallus gallus
Q8AV58
2169
239459
Y2057
D
E
D
I
C
N
K
Y
N
G
A
V
L
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
S2019
S
N
Y
N
G
V
V
S
T
E
S
T
A
L
T
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
E1170
K
Y
S
V
K
D
K
E
D
G
P
M
D
S
E
Fruit Fly
Dros. melanogaster
O97394
2224
246236
E2116
V
A
Y
H
S
D
E
E
S
L
K
C
Y
D
E
Honey Bee
Apis mellifera
XP_623565
2176
242722
K2052
P
P
P
T
M
L
G
K
S
P
P
R
P
S
P
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
M2122
S
R
N
S
G
G
V
M
N
M
Y
G
L
A
T
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
T2790
L
K
A
E
T
S
F
T
L
K
T
K
I
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
0
13.3
N.A.
6.6
6.6
N.A.
0
100
N.A.
0
20
6.6
0
13.3
0
P-Site Similarity:
100
100
13.3
20
N.A.
6.6
6.6
N.A.
20
100
N.A.
6.6
53.3
26.6
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
15
0
0
0
0
22
8
22
8
0
% A
% Cys:
0
0
0
0
22
0
15
8
0
0
0
8
0
0
0
% C
% Asp:
22
0
36
8
15
22
0
0
8
0
0
0
8
8
0
% D
% Glu:
0
22
0
22
8
0
8
22
0
15
0
0
0
0
36
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
22
8
8
0
0
29
0
22
8
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
22
0
15
8
0
0
0
0
0
8
0
8
% I
% Lys:
8
15
0
0
8
0
29
8
15
15
8
8
0
0
0
% K
% Leu:
8
0
0
0
0
8
8
8
15
8
0
0
29
22
15
% L
% Met:
0
0
0
0
8
0
0
8
0
8
0
8
0
0
0
% M
% Asn:
15
8
8
15
0
22
0
15
36
0
15
8
8
0
8
% N
% Pro:
8
8
8
0
0
0
0
0
0
8
15
0
8
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
15
0
0
0
% R
% Ser:
15
15
15
8
8
8
0
8
15
8
22
0
0
15
0
% S
% Thr:
0
0
0
8
8
0
0
8
15
0
8
8
0
29
15
% T
% Val:
8
0
0
8
0
8
22
0
0
0
0
22
0
22
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
15
22
0
0
0
0
22
0
15
15
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _